Many people ask whether dark spots on the hands could signal melanoma. The answer is: sometimes. While most spots are harmless, some can be early signs of this serious skin cancer. Knowing what to watch for and when to see a doctor is essential.

Melanoma begins in melanocytes, the cells that produce pigment. It often appears on the back or legs, but it can also develop on the hands, including the palms or under the nails. The latter is known as subungual melanoma, a less common but important form.

The ABCDE rule helps assess suspicious spots: Asymmetry (uneven shape), Border (irregular edges), Color (varied shades), Diameter (larger than 6 mm), and Evolving (changing over time). Other red flags include itching, bleeding, sudden appearance in adulthood, or a spot that stands out from others.

Still, most dark spots are benign. Common causes include sun exposure, aging, or hormonal shifts. Known as age spots or liver spots, these result from long-term UV damage and natural skin aging, particularly on frequently exposed areas.

Other contributors may include liver issues, hormonal changes like pregnancy or menopause, and nutritional deficiencies. While not always serious, any sudden changes should be checked by a dermatologist to rule out skin cancer or underlying conditions.

Preventive care can lower the risk of developing dark spots. Daily sunscreen use, a diet rich in antioxidants, regular hand moisturizing, and avoiding tobacco or excessive alcohol all support healthier skin and slow visible aging.

Staying vigilant and protecting your skin are key steps in maintaining long-term health and spotting potential issues early.